The World Lymphoma Awareness Day (WLAD) is focusing this year in the diversity of lymphoma. One single word –lymphoma– encompasses more than 60 different diseases. The recognition of this diversity started officially with the publication of the Revised European American Lymphoma (REAL) Classification in 1994, which aimed at defining specific entities according to the morphology, the immunophenotype and the genetic and molecular markers. Crucially, these many different diseases have distinct clinical characteristics, clinical behaviour and prognosis, requiring different management strategies. Stem cell transplantation (SCT), either autologous or allogeneic, is a treatment option that benefits patients with many different types of lymphoma, the difficulty being the identification of the sub-populations of patients that will obtain the greatest benefit. The diversity of lymphoma has hampered research on the role of SCT in patients with lymphoma, given that many sub-types are very rare, precluding big studies. The EBMT Lymphoma Working Party (LWP) has significantly contributed to define the role of SCT in rare types of lymphoma, thanks to the availability of large number of patients with long term data. As an example of many, a recent study of the LWP in patients with hepatosplenic T-cell lymphoma [Allogeneic and autologous stem cell transplantation for hepatosplenic T-cell lymphoma: a retrospective study of the EBMT Lymphoma Working Party. Tanase A et al, Leukemia. 2015 Mar;29(3):686-8] demonstrated graft vs lymphoma activity resulting in long-term survival in patients receiving allogeneic SCT for this uncommon condition.
Furthermore, the commitment of the LWP to continue delineating the role of SCT in rare types of lymphomas is reflected in the programme of the 12th Educational Course of the LWP on "Treatment of Malignant Lymphoma: State-of-the-Art and Role of Stem Cell Transplantation" (Dublin, 21-23 September 2016; #LWPEdCourse16) with sessions and talks dedicated to unusual types of lymphoma such as T-NHL, primary CNS lymphoma and Waldenstrom macroglobulinemia.
Click here to view the programmeFollow-us on @LymphomaWP_EBMT
On the occasion of the World Lymphoma Awareness Day, the EBMT staff members "light it red" for lymphoma to raise awareness of lymphoma and provide hope to those afffected by this cancer.